Presentation description

Heart disease is the leading cause of death globally, with heart failure (HF) as a significant contributor. Patients with HF are at increased risk of arrhythmic death and incidence. HF patients typically do not die from HF itself but from arrhythmias that develop. Uncertainty continues regarding the specific arrhythmic episodes that precede heart failure. Identifying and understanding the progression of arrhythmic incidence prior to arrhythmic deaths could provide early indicators and aid in timely detection and intervention. In this study, a canine subject underwent coronary artery occlusion followed by the implantation of a telemetry device for continuous ECG monitoring. As the subjects the condition progressed to HF, data was collected and analyzed using specialized software. Here, we report the specific incidence of ventricular tachycardia (VT), premature ventricular contractions (PVCs), junctional rhythms, and the specific timing of these arrhythmic events. Continuous monitoring in this canine model of ischemic heart failure effectively identified arrhythmias that precede heart failure, demonstrating the potential for improved early detections and interventions for future models, leading to better clinical outcomes for HF patients.