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Studying Mechanisms that Contribute to Genomic Integrity

Semester: Spring 2024

Presentation description

Cancer develops when DNA damage goes unrepaired and mutations accumulate. Nup50 and its binding partners, Nup153 and RCC1, are all individually required for 53BP1 to initiate repair at DNA damage sites. I tested mutant versions of Nup50 that are deficient in binding either Nup153 or RCC1 to determine whether those interactions play a role in 53BP1 regulation.

Presenter Name: Cameron Davis

Presentation Type: Poster
Presentation Format: In Person
Presentation #B44
College: Medicine
School / Department: Oncological Sciences
Research Mentor: Douglas Mackay
Date | Time: Tuesday, Apr 9th | 10:45 AM