Presentation description

Malaria is caused by the parasite Plasmodium, which infects red blood cells. Thrombocytopenia is a drop in the circulating platelets and is a frequent symptom of malaria. More research is needed to determine the underlying mechanisms of thrombocytopenia in Plasmodium infection.

Possible reasons for thrombocytopenia are 1. consumption and 2. lack of production. Here, we use mouse models of malaria to investigate these possible causes of thrombocytopenia.