Presentation description

Inhaled Corticosteroids (ICs), such as Advair, are among the most common treatments for asthma. Use of ICs in patients can be correlated with voice disorders and vocal fold inflammation in 5-58% of patients. Using experimental and control groups of rabbits, we dosed twice daily with Advair or saline and monitored progression of inflammation of the vocal fold tissue with scoping. Upon harvesting vocal fold tissue we found elevated levels of inflammatory cytokine IL-6 in rabbits receiving Advair.