Presentation description

My project examines DNA proteins MutT and MutY in a rare transversion mutation pathway. MutT prevents an OG mutagen from binding to DNA. MutY exises specific nucleotides that contribute to the mutation pathway.This pathway is important since genetic information is lost from the replacement of nucleotides and the switched placement of pyridine and purine on opposite strands. My hypothesis is that when MutT is inhibited and MutY is included, the highest mutation frequencies should be observed.