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Immunomodulation Improves Cancer Cell Clearance by T Cells During Multi-Antigen T Cell Hybridizer Therapy

Semester: Spring 2024

Presentation description

Treatment of blood cancer is challenging due to the side effects of chemotherapy and cancer relapse. Multi-antigen T cell hybridizer (MATCH) therapy is a novel treatment system from our research group which directs a patient's own T cells to eliminate their cancer cells. However, T cells become exhausted during such therapy, losing their function. This research examines T cell exhaustion and explores several methods of reducing it, demonstrating that PD-1 and IL-10 blockades successfully do so.

Presenter Name: Isaac Kendell

Presentation Type: Oral
Presentation Format: In Person
College: Engineering
School / Department: Bioengineering
Research Mentor: Jindřich Kopeček
Date | Time: Tuesday, Apr 9th | 1:00 PM
Physical Location or Zoom link:

Union Collegiate Room