Presentation description

Hepatocellular Carcinoma (HCC) is the most common form of liver cancer in the United States. Inflammation is a key factor in the progression from fatty liver disease to HCC, so pro-inflammatory pathways such as the NF-kB pathway have been studied. I studied the colocalization of HAF and other key proteins in the pathway to determine if there is any transcriptional regulation occurring in the nucleus. I also studied HCC cells in a hypoxic environment to determine the impact of HIF on the pathway.