Presentation description

Salmonella Pathogenicity Island 1 (SPI1) is a region of the Salmonella chromosome that codes for the genes necessary to build a type 3 secretion (T3S) injectisome system. My research aims to develop new genetic tools in order to facilitate the study of the SPI1 injectisome system. What is needed for the characterization of SPI1 secretion mechanisms is the development of reporters that allow for selection of protein substrates through the injectisome T3S system to the outside medium.