Presentation description

This research investigates antibody-ligand chemistry, crucial in the immune response. Stoichiometry and ligand accessibility on porous silica particles analyzed via Raman microscopy, allowing label-free quantification of binding. Silica particles with lipid bilayers enable detection of modest ligand fractions. Density variation influences antibody capture. The use of FAB fragments are used to determine binding stoichiometry of full antibodies.