Presentation description

Malaria is a significant problem across the world with over 200 million clinical cases annually. However, majority of infections (>75%) can be resistant or asymptomatic (without overt symptoms).Preliminary findings utilizing wild derived Mus musculus, housed in SPF conditions,demonstrated a wide range of anemia and innate immune reactivity after Plasmodium infection,indicating that that genetic diversity in mice can be used to uncover the immunological mechanisms underlying asymptomatic malaria.