Presentation description

The morbidity and mortality of lung cancer can be attributed to its invasion and metastasis capabilities. My project strives to identify mechanisms that propel the invasion of lung adenocarcinoma. The Extracellular Signal-Regulated Kinase (ERK) is hyperactivated in solid tumors including lung cancer and drives oncogenesis. To understand how ERK controls lung cancer invasion, it must be studied in a 3D environment that represents the complex extracellular matrix and structure of the lung.