Faculty mentor: Kent Lai
Phosphoglucomutase 1 (PGM1) deficiency is a metabolic disorder caused by mutations in the PGM1 genes. PGM1 deficiency is extremely dangerous in infancy and leads to the malfunction of several organs. However, because it is so rare, PGM1 deficiency has not been well studied. The purpose of this project is to genotype a mouse model focusing on PGM2, which is the isoenzyme of PGM1, in mice.
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