Poster 90: Ria Kaddu – Intrauterine Growth Restriction and Supplemental DHA Alter Rat Hepatic Histone Methylation

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Faculty mentor: Lisa Joss-Moore

My project examines the sex-divergent pattern of histone methylation in IUGR rats. Intrauterine growth restriction (IUGR), or the inability of the fetus to achieve its full growth potential, dysregulates circulating docosahexaenoic acid (DHA) in the fetus and neonate. DHA is a fatty acid important for development in the neonate. IUGR dysregulates hepatic function and one-carbon metabolism. This project aims to understand how IUGR and supplemental DHA alter hepatic histone methylation in the rat.

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Questions or comments? Contact me at: u0791821@utah.edu


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