Faculty mentor: Ryan Looper
The TAN 1057 family of compounds show promising biological activity. This project involves the synthesis of a TAN 1057-D inspired heterocyclic core. A modular synthetic strategy has been implemented to construct the heterocyclic core of TAN 1057-D. The core has been synthesized through the utilization of Ullmann copper(I) chemistry, and core manipulation is in progress to allow for analog development. Synthesis of analogs will inform the structural characteristics of a future drug candidate.
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