Faculty mentor: Martin Horvath
The macula of the human eye is enriched in carotenoids, antioxidants capable of protecting against light damage. The carotenoid zeaxanthin and its protective functions is controlled by the protein, GSTP1. I am working towards determining the structure of zeaxanthin in complex with GSTP1 to reveal the molecular interactions critical for the protection of the eye and elucidate its role in the prevention of ocular diseases.
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