Faculty mentor: Minna Roh-Johnson
Tumor cell metastasis is the leading cause of death among cancer patients, but the mechanism by which tumor cells migrate in-vivo is poorly understood. With focus on the dynamic behavior of focal adhesions in-vitro, we chemically inhibited FAK to study the effects of focal adhesions in-vivo. The observed reduction in cell metastasis following treatment of melanoma cells suggests a promising avenue of study to better understand the role that focal adhesions have on metastasis in-vivo.
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