Faculty mentor: Melodie Weller
Persistent low-level infections of the Hepatitis Delta Virus (HDV) have been suggested to lead to primary Sjogren’s syndrome development. A study was designed to identify whether progesterone, B-estradiol, and DHEA affect the expression of the HDV antigen in an in-vitro system. No significant changes were observed with progesterone and B-estradiol. DHEA exhibited a dose-dependent increase in HDV antigen transcript.
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