Faculty mentor: Joel Harris
An increased molecular-level understanding of protein ion-exchange interactions is essential for progress in the field of protein purification. In this work, we analyze selective protein adsorption to a model positively-charged ion-exchange material consisting of net positively-charged lipid bilayers formed within reversed-phase silica particles. We utilize confocal Raman microscopy for individual particles to obtain structural and quantitative information about the properties of this surface.
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