Dr. Hwang is an MD PhD studying retinal detachment, which affects 1 in 200 Americans and frequently causes permanent visual impairment. Vitreous abnormalities lead to retinal detachment, but the pathway involved is poorly understood. There is a critical need to characterize vitreous abnormalities in conditions which predispose to retinal detachment. Our laboratory uses genetic mouse models of Stickler syndrome and aged wild-type mouse to test the hypothesis that vitreous structural abnormalities lead to retinal detachment. We anticipate that by investigating underlying vitreous abnormalities, we can devise more effective ways to prevent retinal detachment.
Keywords: ophthalmology, retina, eye, laboratory, microscopy, imaging, dissection, animal