Understanding Structural Birth Defects

Faculty Name:
Luca Brunelli


Faculty College:


Project Description:

We are developing novel, DNA engineering, genetic and therapeutic approaches for structural birth defects, including congenital diaphragmatic hernia (CDH), a severe anomaly that typically presents in newborns. CDH still has high mortality and therapeutic approaches are currently limited.

Opportunity Type:

Volunteer; Earn independent study credit; Prepare a UROP proposal; Write an Honors Thesis; This is a work-study position

Student Role:

Work in the lab doing molecular biology techniques or analyzing next-generation sequencing data or being involved in a therapeutic animal and human trial in CDH.

Student Benefits:

Be exposed to a broad spectrum of techniques and methodologies, including the latest developments in DNA engineering (Lyozin T.G. et al. Nature Methods 2014) and genetics.

Project Duration:

The project is ongoing but a section of this project can be completed over a summer. About 20-40 hours per week.

Minimum Requirements:

Biochemistry or molecular biology or genetics or animal work or human trials