Understanding Structural Birth Defects

Faculty Name:
Luca Brunelli

Department:
Pediatrics

Faculty College:
Medicine

Email:
luca.brunelli@genetics.utah.edu


Project Description:

We are developing novel, DNA engineering, genetic and therapeutic approaches for structural birth defects, including congenital diaphragmatic hernia (CDH), a severe anomaly that typically presents in newborns. CDH still has high mortality and therapeutic approaches are currently limited.



Opportunity Type:

Volunteer; Earn independent study credit; Prepare a UROP proposal; Write an Honors Thesis; This is a work-study position


Student Role:

Work in the lab doing molecular biology techniques or analyzing next-generation sequencing data or being involved in a therapeutic animal and human trial in CDH.


Student Benefits:

Be exposed to a broad spectrum of techniques and methodologies, including the latest developments in DNA engineering (Lyozin T.G. et al. Nature Methods 2014) and genetics.


Project Duration:

The project is ongoing but a section of this project can be completed over a summer. About 20-40 hours per week.


Minimum Requirements:

Biochemistry or molecular biology or genetics or animal work or human trials