We will investigate a new mouse model of inactivity-induced obesity and determine whether long-term inactivity induce changes in skeletal muscle mitochondria phospholipid composition; thus, affect the mitochondria’s capacity for oxidative phosphorylation. Understanding the role of mitochondrial phospholipids in regulating respiratory efficiency and energy metabolism could provide novel therapies to treat the current obesity epidemic.
Physical Therapy and Athletic Training
Volunteer; Prepare a UROP proposal; Write an Honors Thesis; Earn independent study credit
Mouse handling, measure body composition, lean mass, etc., understand how research is conducted and be in charge of a project from start to finish.
Gain valuable insight into the research process, opportunity to be published in a journal, critical thinking and troubleshooting skills.
6-8 weeks per cohort of mice; potentially multiple cohorts. Minimum of 6-8 hours per week depending on tasks; flexible (to an extent) as needed.
Ideally upperclassmen, dedicated, reliable, science/pre-med major and/or some basic biology courses. Passion for research and natural curiosity is a bonus.