Translational Research in Pediatric Traumatic Brain Injury using a Rat Pup Model with a focus on Neuroinflammation and Docosahexaenoic Acid

Faculty Name:
Michelle Schober


Faculty College:


Project Description:

The Schober lab focuses on neurologic outcomes after traumatic injury (TBI) to the developing brain, using a rat pup model. The Schober lab has studied Docosahexaenoic Acid (DHA), a component of fish oil, and published novel findings on how inflammation in the developing rat brain responds to injury with or without treatment with DHA. Ongoing work highlights sex-dependent differences and functional aspects of the brain’s immune cells, such as the ability to make reactive oxygen species and phagocytose beads.

Opportunity Type:

Volunteer; This is a paid research position; Prepare a UROP proposal; Write an Honors Thesis or Senior Thesis

Student Role:

handling rat pups, helping with surgery and rat pup care, helping with bench work such as histology (slicing brain, staining, imaging) and flow cytometry preparation

Student Benefits:

learning about translational science. Potential publication. Working with Physician Scientist, shadowing opportunities for medical school interested students. mentoring.

Project Duration:

four year project, but smaller goals are accomplished often in weeks. Hours are flexible because they would help an existing lab specialist.

Minimum Requirements:

professionalism, willingness to learn, trustworthiness to finish what is started