The most common and destructive form of clinical peripheral nerve injury is due to rapid-stretch trauma. Neuroma-in-continuity (NIC) is a pathophysiologic outcome frequently associated with these injuries, and aberrant inflammation may contribute to this pathophysiology by orchestrating a microenvironment that inhibits axonal regeneration. This project aims to modulate inflammation through therapeutic agents with the hope of preventing neuroma formation and associated neurologic deficits.
OUR Certified Mentor
Volunteer; This is a work-study research position; Prepare a UROP proposal
Students will primarily assist in histologic techniques such as tissue processing, IHC staining, microscopy/imaging, and data/image analysis with the potential for expansion.
Basic/translational research experience and skills. Potential to learn surgical and tissue harvest techniques, and expansion to other projects. Opportunity for publication.
5-10 hours/week for project duration, through FY of July 2023, but we have numerous ongoing projects. Multiple semester involvement. Commitment/flexibility can be discussed.
1. Good work ethic 2. Reliable 3. Good personal and communication skills 4. Interest in neuroscience, neurotrauma, translational research, medicine