Investigating Mitochondrial Nutrient Transporters upon Metabolic Reprogramming

Mentor Name:
Zachary Wilson

Mentor Position:
OUR Certified Mentor




Project Description:

The loss of nutrient homeostasis is a primary feature of many age-associated diseases including diabetes, neurodegeneration, and cancer. In the Adam Hughes lab we use yeast and mammalian cell systems to investigate how nutrient excess negatively impacts a variety of cellular organelles to drive aging and disease. We’re seeking a highly motivated student to investigate a recently discovered pathway that selectively removes mitochondrial nutrient transporters to protect cells from metabolic overload and nutrient toxicity.

Opportunity Type:

Volunteer; Prepare a UROP proposal; Write an Honors Thesis or Senior Thesis; Earn independent study credit

Student Role:

Students will work with a postdoctoral fellow to learn and perform fundamental laboratory experiments required for genetic, biochemical, and cell biological analyses.

Student Benefits:

Engage with a diverse biomedical research group to garner experience necessary to compete for future opportunities in scientific research and professional schools.

Project Duration:

Project is ongoing. Students are expected to perform research 10-15 hours per week.

Minimum Requirements:

Completion of the following courses or equivalent is preferred (CHEM1210 &1220, BIOL1610 & 2020)