Effect of e-cigarette vapor on flavor preference: establishing an animal model

Faculty Name:
Matt Wachowiak

Neurobiology & Anatomy

Faculty College:


Project Description:

Performing behavioral assays in mice that test whether exposure to nicotine vapor paired with an odor, mimicking the experience of e-cigarette usage, generates a preference for seeking out that odor in mice. This would allow us to establish the mouse as a useful animal model for ultimately understanding the neural mechanisms by which flavor additives may drive a preference for e-cigarette usage and subsequent nicotine addiction.

Opportunity Type:

Volunteer; Earn independent study credit; Prepare a UROP proposal

Student Role:

Handling mice in the context of simple behavioral assays (no invasive procedures are involved). Testing new behavioral paradigms. Data analysis.

Student Benefits:

Experience in rodent behavioral assays, experiment design and data analysis. Introduction to systems neuroscience.

Project Duration:

2 semesters; minimum 10 hours per week.

Minimum Requirements:

comfort in handling live mice. Should be able to analyze data (i.e., in Excel) and reliably record measurements and summarize Results.