Diabetes Research with a Cardiac Focus using Animal Models

Faculty Name:
Candace Reno

Internal Medicine

Faculty College:


Project Description:

I study hypoglycemia (low blood sugar) as a complication in the treatment of diabetes. My main research project is understanding the mechanisms of hypoglycemia-induced cardiac arrhythmias in rodent models. The goal of this project is to determine potential therapeutic targets to prevent sudden death due to hypoglycemia in people with type 1 diabetes. Additionally, I study how repeated episodes of hypoglycemia increase the risk of cardiac damage during a subsequent myocardial infarction induced experimentally.

Opportunity Type:

Volunteer; Prepare a UROP proposal; Write an Honors Thesis or Senior Thesis; Earn independent study credit

Student Role:

Students will learn rodent survival surgery, hypoglycemia "clamp" experiments, tissue harvesting and staining, protein analysis and data analysis and manuscript writing.

Student Benefits:

Students will learn hands on how to design and execute experiments in a clinically relevant field with potential for authorship on abstracts and manuscripts.

Project Duration:

Each project is for one semester at a time with potential for additional semesters. 10 hour/week.

Minimum Requirements:

Basic biology courses