Development of an in vitro and in vivo model for cholesteatoma

Mentor Name:
Albert Park

Mentor Position:
Professor

Department:
Surgery

College:
Medicine

Email:
albert.park@hsc.utah.edu


Project Description:

We would like to characterize the pathophysiology of cholesteatomas, a leading cause of hearing loss. We will obtain patient samples of cholesteatomas and attempt to grow this tissue in vitro. We will then perform gene and cytokine studies to characterize its behavior. Hopefully this approach will provide avenues to assess efficacy of several potential drugs.



Opportunity Type:

This is a paid research position; This is a work-study research position; Prepare a UROP proposal; Write an Honors Thesis or Senior Thesis; Earn independent study credit


Student Role:

Student will be expected to review the medical literature on this subject, create the in vitro model for cholesteatoma and perform the gene and cytokine studies.


Student Benefits:

Hands on experience of a clinically significant problem.


Project Duration:

Project may become long-term although we are flexible. We seek independent and motivated students.


Minimum Requirements:

If you are hard working and good, we will work with your schedule.