Poster #14: Sonresa Ochoa-Vidales – Evolutionary Analysis of Host-Pathogen Adaptations in MDA5

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Faculty mentor: Nels Elde

I uncover novel host-pathogen conflicts in mammalian virus-detecting innate immune proteins. I specifically, am investigating signals of rapid evolution I have identified in the gene, MDA5, which is responsible for inducing interferon (IFN) expression of the host’s innate immune response when activated by unknown dsRNA. I am currently designing experiments to assess the functional significance of the amino acid changes we observed across species’ MDA5.

Click below to hear me present my poster!
Questions or comments? Contact me at: u1168474@utah.edu

 

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