Faculty mentor: Micah Drummond
Voluntary wheel running (VWR) is a therapeutic tool that mimics exercise in humans will allow us to understand how muscle macrophages function during muscle regrowth following disuse. We hypothesize that VWR will improve muscle recovery in young mice and that will correspond to increased macrophage abundance and an increased transcriptional signature for chemokine expression. In order to test this hypothesis, we employed a mouse model to imitate disuse and recovery with and without VWR.
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