Faculty mentor: Thomas Zangle
We validate the use of microwell arrays as a platform for digital cell growth assays. This approach shows improvements over traditional bulk cell counting assays by capturing cell-to-cell heterogeneity information in addition to population-based averages. To ensure accessibility, imaging was conducted manually at three time steps. Experiments with both nonadherent and adherent cell lines validate population-based measures of doubling time while showing the spread of individual cell growth rates.
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