Faculty mentor: Catherine Loc-Carrillo
We investigated the efficacy of phage-antibiotic combination (PAC) treatments against in vitro, dual-species biofilms consisting of methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. We found that antibiotic type, concentration, and timing all play a significant role in PAC treatment efficacy. Contrary to existing literature, PAC treatments typically performed worse than antibiotics alone, which may be due to the alternative wound-like medium used in the study.
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