Faculty mentor: Micah Drummond
The goal was to better understand how miR146a effects muscle atrophy and regrowth we have conducted experiments and analysis on muscle tissue in mice that are deficient in miR146a, that have been exposed to hindlimb unloading (muscle disuse) and following 7-day ambulatory recovery after hindlimb unloading. We hypothesize that the absence of miR146a mice will be insulin resistant and have excessive muscles loss during disuse and impaired muscle regrowth and following disuse when reambulating.
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