Faculty mentor: Anna Beaudin
This research looks at how maternal immune activation affects the innate lymphoid cells in the small intestine of mice. In this model, MIA is induced using poly(I:C), a double stranded RNA molecule. Our hypothesis is that the poly(I:C) treated mice will show an increased cellularity in all three ILC subtypes compared to controls. Our data so far shows increased cellularity in the ILC2s and ILC3s in the small intestine, but not in the ILC1s. Therefore, our hypothesis is not fully supported.
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