Faculty mentor: Diego Lopez
I research the effects of maternal immune activation (MIA) on early lung immune cell establishment from postnatal day 3 to day 11. Alterations in the early lung immune environment may contribute to risk of developing allergic asthma. I hypothesized that MIA would increase the rate of immune cell infiltration in this environment. Preliminary data indicates that MIA drives ILC2 expansion and increases levels of cytokines IL-5 and IL-13, which may increase susceptibility to asthma.
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